What is cftr full gene sequencing? ?

CFTR Full Gene Sequencing is a comprehensive genetic test that examines the entire coding region of the CFTR gene. This gene is responsible for producing a protein that regulates the movement of salt and water in and out of cells. Mutations in the CFTR gene cause Cystic Fibrosis (CF), a serious genetic disorder affecting the lungs and digestive system.

This test detects both common and rare mutations, making it more accurate than basic CF carrier screening.

Why is cftr full gene sequencing important in dubai? ??

✔️ High carrier rate in Middle Eastern populations
✔️ Essential for couples planning for pregnancy
✔️ Important for diagnosing atypical CF symptoms
✔️ Helps in targeted treatment planning
✔️ Useful for IVF and genetic counseling

Who should take the cftr gene test? ?‍?‍?‍?

• Couples undergoing fertility treatments

• Individuals with a family history of Cystic Fibrosis

• Newborns with positive IRT screening

• Individuals with unexplained respiratory or digestive symptoms

• Anyone planning for prenatal screening or PGD

Test methodology ?

1. Sample collection: Blood or saliva sample

2. DNA extraction: High-quality DNA is extracted from the sample

3. Next-Generation Sequencing (NGS): Full sequencing of all 27 exons and intron-exon boundaries of the CFTR gene

4. Bioinformatics analysis: Identification of known and novel CFTR mutations

5. Report delivery: Detailed genetic report with clinical interpretation by certified geneticists

? Turnaround time: 10–15 working days
? Report includes: Variant classification, clinical relevance, inheritance risk, and recommendations

Advantages of cftr full gene sequencing ✅

✨ Detects more mutations than panel testing
✨ Highly accurate & comprehensive
✨ Suitable for carrier screening, diagnosis, and treatment planning
✨ Non-invasive & safe
✨ Approved by international genetic societies

Faqs ?

what is the cost of cftr full gene sequencing in dubai?
? The cost typically ranges between AED 2,000 to AED 4,000 depending on the lab and if genetic counseling is included.

is this test available for newborns in dubai?
? Yes, newborns can be tested if there's a positive result from initial screening or family history.

how accurate is cftr full gene sequencing?
? Over 99% accuracy in detecting CFTR mutations, including rare and novel ones.

can this test be done for couples before pregnancy?
?‍❤️‍? Absolutely. It is highly recommended for carrier screening in couples before planning a baby.

where can I do this test in dubai?
? Many top genetic labs and hospitals in Dubai offer CFTR full gene sequencing. We can help you book the most trusted centers.

Conclusion ?

CFTR Full Gene Sequencing is a gold-standard genetic test for detecting mutations that cause Cystic Fibrosis. With its high accuracy, clinical utility, and growing demand in the UAE, especially Dubai, it is an essential tool for early diagnosis, carrier screening, and reproductive planning.

Whether you're planning a family, dealing with unexplained symptoms, or looking for answers in your child’s health condition—this test can provide the insights you need.

? Early testing = Early action = Better health outcomes.